Botox & the corners of the mouth – what does the treatment do, and when does it work?
The corners of the mouth can be lifted with Botox. The treatment relaxes the muscles that pull the corners of the mouth downward. Botox treatment subtly and naturally rejuvenates and refreshes the appearance.
The effects of Botox treatment begin within a few days and usually last 3–6 months. If there are also deep lines around the corners of the mouth, or if the support around the corners of the mouth has diminished with age, the treatment is often supplemented with fillers.
What does Botox for the corners of the mouth mean?
Botox for the corners of the mouth involves injecting botulinum toxin into the depressor anguli oris muscle (DAO muscle).
DAO muscles
- turn the corners of their mouths downward
- can give the lower face a sad or tense expression
When the muscles relax, the downward pull on the facial features decreases. When the muscles that pull the facial features upward take over, the corners of the mouth lift slightly.
It’s not about filling or reshaping, but about correcting muscle imbalance.
What does the final result look like?
Botox does not lift the corners of the mouth in the same way as surgery. The typical effect is subtle.
The end result often looks like this:
- An angry or sad expression becomes more neutral
- The corners of my mouth don't droop as much as they used to when I'm at rest
- The lower part of the face looks rested and more youthful than before
The change is small but often very significant.
When is Botox for the corners of the mouth not enough?
This is a key clinical point. There are many causes of aesthetic problems in the corner-of-the-mouth area.
Changes in the area around the mouth may be related to, for example
- DAO muscle activity
- loss of volume
- sagging skin
Botox affects only the first of these.
Filling material at the corners of the mouth – a different mechanism
Fillers (usually hyaluronic acid in practice) work differently than Botox.
They do not relax the muscle but instead lift the corners of the mouth.
The filler can
- restore the tissue's fullness
- support drooping corners of the mouth
- smooths and reduces marionette lines
The filler therefore does not affect the direction of muscle contraction, but rather the skin, subcutaneous tissue, and the skin’s supporting structure.
Botox or fillers for the corners of the mouth?
Botox is a better option when
- the corners of the mouth turn downward when smiling or at rest
- Muscle activity is a clear cause of the change in facial expression
- We want a subtle change without adding volume
The filler works better when
- the lines are deep
- There is a shortage of volume in the area
- the skin has become saggy
Combination therapy: often the best outcome
In many cases, the best results are achieved by combining Botox and fillers.
- Botox reduces the downward pulling force of the muscles.
- The filler supports the corners of the mouth and reduces marionette lines.
The combination of dermal fillers and Botox is often beneficial, especially when the area around the corners of the mouth shows both excessive activity of the downward-pulling muscles and a loss of tissue support and fullness.
Botox for the corners of the mouth, price
- Botox, corners of the mouth: €270
- Filler, corners of the mouth: €450
- Combination treatment: €550
The final treatment decision is made on an individual basis during the consultation, taking into account the client’s wishes and their current condition.
When will the results be available?
The first effects are usually noticeable within 3 to 7 days. The full effect is typically observed after about two weeks.
How long does the effect last?
Botox in the corners of the mouth usually lasts 3 months. Fillers in the corners of the mouth last 6–12 months. The duration varies from person to person.
Author and Expertise
Author: Ville Männistö
Title: Oral and Maxillofacial Surgeon, Aesthetic Medicine
In addition to his clinical work, Ville Männistö is also a doctoral researcher. Part of his doctoral research focuses on the use of botulinum toxin. The research findings have been published; see the PubMed database.
Specialties: Botox and dermal filler treatments for the face
Last updated: 2026
