Botox for Migraines – Effectiveness, Cost, and Experiences

Botox and Migraines: A Summary

  • Studies have shown that Botox, or botulinum toxin, is effective in preventing chronic migraines.
  • This treatment is used especially when migraines occur on at least 15 days a month.
  • Botox treatments are usually administered every 12 weeks.
  • Injections are administered in the head and neck area at points 31–39.
  • About half of patients experience significant relief from their migraine symptoms as a result of the treatment.
  • Botox is a medication covered by Kela for the treatment of chronic migraine.
  • Price: €290–690
    • Payment methods at the clinic: credit card, cash, contactless payment
    • Payment methods in the online store: bank transfer, credit card, mobile payment, invoice, installment plan

Does Botox help with migraines?

Yes. Studies show that Botox treatment reduces the number of headache days in people with chronic migraine and can improve quality of life. However, the treatment does not work the same way for everyone. An individual response to treatment becomes apparent after the first Botox treatment.

"Nearly all of my patients with migraines and tension headaches have benefited from their Botox treatments," says Dr. Laura Juopperi, who has also found relief from her own migraines through Botox treatment.


Botox for the treatment of migraines

Botox, or botulinum toxin, is quite effective for the preventive treatment of chronic migraine. Chronic migraine is defined as experiencing headaches on at least 15 days per month. Migraine patients constitute a small but heavily burdened patient group, and treating them is challenging.
Migraine is not a single condition but a group of different types of headaches. During the consultation, the most important thing is to distinguish migraine from, for example, tension headaches or medication-overuse headaches. Only then can we determine which treatment options are appropriate.

What is chronic migraine?

Chronic migraine refers to a condition in which headaches occur on at least 15 days per month and migraine features are present on at least eight days per month. Chronic migraine differs from typical episodic migraine in terms of both the number of symptoms and the need for treatment.

How does Botox affect migraines?

In addition to the neuromuscular junction, botulinum toxin also affects pain pathways. It reduces the release of neurotransmitters at nerve endings, which can dampen the transmission of pain signals.

Botulinum toxin treatment for migraines involves the use of small doses of botulinum toxin. The doses are injected into the muscles of the head and neck according to a precisely defined protocol.

In practice, treatment is administered at several sites:

  • on the forehead
  • on the temples
  • the back of the head
  • the neck and shoulder area

In addition to the muscles, the treatment targets the nerve endings involved in the development of headaches.

What do studies show about Botox treatment for migraines?

The benefits of botulinum toxin in chronic migraine have been demonstrated in several randomized trials. The average benefit is moderate, but some patients experience a response to treatment that is significantly greater than average.
(Surgeon Ville Männistö)

Two large-scale PREEMPT studies (involving over 1,300 patients) provide key evidence for the use of botulinum toxin therapy in the prevention of chronic migraine.

In these studies

  • The number of days with headaches decreased more than with a placebo
  • the number of days with severe headaches decreased
  • On average, the difference was about 1.8 days per month

Does Botox completely cure migraines?

A realistic goal for migraine preventive treatments is

  • a reduction of approximately 50% in the number of episodes
  • relief of symptoms

Botox may provide some relief. For some patients, the response is clearly better than average, but the predictive factors are not yet known.

Botox is not a miracle cure for migraines, but for the right patient, it is a significant part of an effective treatment plan.
(Surgeon Ville Männistö)

How quickly does Botox help with migraines?

The effects of Botox treatment do not begin immediately after the injections.

Typically

  • The first effects will be noticeable within 1–2 weeks
  • Optimal results are achieved after 2–3 treatment sessions

Treatment is usually repeated every 12 weeks.

What are patients' experiences with botulinum toxin treatment for migraines?

Botulinum toxin treatment for migraine has long been used to treat chronic migraine.

Patients often describe, for example,

  • a reduction in the number of migraine days
  • relief of symptoms
  • greater ability to function in daily life
  • less need for emergency medication

However, the treatment does not work equally well for everyone, and its effectiveness is usually assessed after a few rounds of injections.

For a couple of my migraine patients, Botox treatment has worked so well that they’ve been able to stop taking the biologic medication they were previously using. Such a good response to treatment is, of course, an exception; generally, Botox treatment is just one part of a migraine patient’s overall treatment plan.
(Dr. Laura Juopperi)

Aninka's experiences with botulinum toxin treatment for migraines

Aninka underwent extensive medical botulinum toxin treatment, which alleviated
the symptoms of both migraines and bruxism.

Thanks to Ville for the great service and, above all, for the effective help with my migraines! 🙂
A Migraine Sufferer’s Experiences, November 13, 2024

Who is a good candidate for botulinum toxin treatment for migraines?

Botulinum toxin treatment is not a first-line treatment for migraine. It is generally used when a patient has been diagnosed with chronic migraine and other preventive treatments have not provided sufficient relief or are not suitable for the patient.

Chronic migraine refers to a condition in which headaches occur on at least 15 days per month. The efficacy of botulinum toxin treatment has been demonstrated specifically in this patient group.

Botulinum toxin treatment may be considered, for example, when:

  • The migraine has become chronic
  • I have a lot of days with headaches
  • Preventive medication is not effective enough
  • Preventive medication causes side effects
  • Other preventive treatments are not suitable for the patient

According to studies, the efficacy of botulinum toxin in episodic migraine is no different from that of a placebo. For this reason, the treatment is primarily used for chronic migraine.

Botox treatments are generally not performed if:

  • The patient has a specific neuromuscular disorder
  • the patient is pregnant or breastfeeding
  • There is an active infection at the injection site
  • the patient is allergic to botulinum toxin or the drug’s excipients

In some cases, botulinum toxin has also been tried for the treatment of other severe headache conditions. In clinical practice, some patients suffering from cluster headaches (Horton’s neuralgia) have found relief from the treatment, but botulinum toxin therapy is not an established treatment method for Horton’s neuralgia.

How much does Botox treatment for migraines cost?

The cost of Botox treatment for migraines at VM Aesthetics €290 to €690. The final price depends on whether the patient purchases the botulinum toxin medication themselves or uses the medication provided by the clinic.

  • €290 – treatment using the patient's own medication
  • €690 – treatment with the clinic’s medication (Botox® 200 U)
  • You can pay for the procedure at the clinic or through the online store; the online store offers a wide range of payment options korttimaksamisesta laskuun ja osamaksuun

For the treatment of chronic migraine, botulinum toxin may be covered by Kela based on a doctor’s assessment. In such cases, the patient can obtain the medication from a pharmacy with a prescription and bring it to the appointment.

Treatment is typically repeated every 12 weeks, so the annual cost depends on the number of treatment sessions and whether the patient uses their own medication or medication provided by the clinic.

Is botulinum toxin treatment for migraines covered by Kela?

Yes. Botulinum toxin is a medication covered by Kela for the treatment of chronic migraine when prescribed by a doctor. at VM Aesthetics Dr. Laura Juopperi provides diagnoses and writes prescriptions.

If you have been diagnosed with migraines but don't have a Botox prescription, you can get started by contacting us

You can also schedule an appointment for a free consultation with Dr. Laura Juopperi.

What are the side effects of Botox treatment?

The most common side effects are

  • mild tenderness at the injection site
  • a small bruise
  • temporary neck stiffness

For more information, click here: Side effects of Botox treatment.

Frequently Asked Questions

Is Botox for migraines the same as cosmetic Botox?

No. In botulinum toxin treatment for migraines, the injection sites, dosages, and treatment goals differ from those in cosmetic Botox treatments. When treating migraines, botulinum toxin is injected into the head and neck area according to a precisely defined treatment protocol.

Does Botox help with migraines?

Yes. Studies show that botulinum toxin reduces the number of headache days in people with chronic migraine and may lessen the severity of migraine attacks. However, the response to treatment varies from person to person.

Who is a good candidate for botulinum toxin treatment for migraines?

Botulinum toxin treatment is typically used to treat chronic migraine when headaches occur on at least 15 days a month and other preventive medications have not been sufficiently effective.

How quickly does Botox help with migraines?

The first effects usually begin to appear within 1–2 weeks of treatment. The best response to treatment is often not achieved until after 2–3 sessions.

How often is Botox treatment for migraines performed?

Treatment is usually repeated every 12 weeks or so. More frequent treatment does not generally improve outcomes and may increase the risk of antibody formation.

How long do the effects of Botox treatment for migraines last?

In most patients, the effect lasts for about three months, which is why treatment is usually repeated every 12 weeks.

Can Botox completely prevent migraine attacks?

In some patients, migraine attacks may decrease significantly, but for most, the goal is to reduce the number of headache days and the severity of symptoms.

Does Botox work for regular migraines?

The research evidence particularly supports the treatment of chronic migraine. In episodic migraine, studies show that the efficacy of botulinum toxin does not differ significantly from that of a placebo.

What are the side effects of Botox treatment for migraines?

The most common side effects are tenderness at the injection site, minor bruising, and temporary neck stiffness. Serious side effects are rare.

Why do I have extra headaches after Botox treatment for migraines?

Headaches are a common side effect of botulinum toxin treatment. After botulinum toxin treatment, changes occur in both muscle activity and the transmission of pain signals.

During the first couple of weeks, it is common for changes in muscle function to cause additional headaches. If this does not go away within two weeks, you should contact your healthcare provider.

(Dr. Laura Juopperi)

Is botulinum toxin treatment for migraines covered by Kela?

Yes. Botulinum toxin is a medication covered by Kela for the treatment of chronic migraine, provided that the treatment is prescribed by a doctor and the eligibility criteria are met.

How much does Botox treatment for migraines cost?

The price depends on the amount of botulinum toxin used, the scope of the treatment, and any reimbursement from Kela.

  • With Kela coverage, the botulinum toxin treatment costs about 220–250 euros.
  • If the annual copayment limit—that is, the medication cap—has been exceeded, the cost of the medication is 2.50 euros.
  • Injection therapy at our clinic costs 290 euros.
  • If Botox treatment for migraines is performed using a medication from VM-estetiikka, the treatment costs 690 euros.

The final cost will be estimated at the reception desk.

Can Botox treatment for migraines also help with tension headaches?

Botulinum toxin is primarily used to treat chronic migraine. The evidence for its use in treating tension-type headaches is considerably weaker, and it is not routinely used for this purpose.

"However, many of my patients with tension headaches have found Botox to be a significant help," Laura says.

Where is botulinum toxin treatment for migraines performed?

Medical botulinum toxin treatments are performed at healthcare facilities, such as at VM Aesthetics. A doctor makes the diagnosis and writes the prescription.


Author of the article

This article is based on an interview with Ville Männistö and Laura Juopperi.

Laura Juopperi isa general practitioner specializing in psychiatry who has extensive clinical experience with botulinum toxin treatments.

Ville Männistö is an oral and maxillofacial surgeon certified to perform botulinum toxin treatments.

In addition to his clinical work, he is also a doctoral researcher. Part of his doctoral research focuses on the use of botulinum toxin. The research findings have been published; see the PubMed database.

Last updated: August 11, 2026

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